Research in Focus: Lynnie Correll 

Research in Focus: Lynnie Correll 

Research in Focus shines a light on the innovative studies and discoveries taking shape across the UBC Department of Anesthesiology, Pharmacology & Therapeutics. Through each feature, we celebrate the minds driving meaningful change in research, education, and clinical practice across anesthesiology, pharmacology, and therapeutics. 

For many children and teens, medical procedures can be an experience overwhelmed with stress, uncertainty, and fear. Dr. Lynnie Correll is working to make those moments more manageable and empowering for children and their families. 

Dr. Correll’s research centres around better understanding how Integrative Medicine techniques and therapies can help children and adolescents cope with the stressors associated with medical procedures and surgery. While it is well understood that preparing for, undergoing, and recovering from procedures can be both physiologically and psychologically challenging, there are virtually no evidence-based programs designed to improve this experience for young patients. 

To fill this gap, Dr. Correll is leading a study that brings together patients, caregivers, and clinicians to co-design a first-of-its-kind mobile app aimed at helping families prepare for these stressors. Funded by the Society for Pediatric Anesthesia Young Investigator Award, the project unfolds in two phases. The first uses focus groups and a Modified Delphi process to identify which integrative techniques should be included. The second phase focuses on building the app itself, creating a tool that could transform how young patients experience medical care. 

“I hope that this app will empower children, adolescents, and families in BC and the Yukon (and beyond) by giving them more agency over how their bodies respond to periprocedural stress.”  

— Lynnie Correll, Clinical Assistant Professor, UBC 


Meet Lynnie Correll! 

SiteBC Children’s Hospital (BCCH) 

Rank: Clinical Assistant Professor 

Dr. Correll came to pediatric anesthesia by a somewhat scenic route. Always passionate about research, she initially planned to attend graduate school after college. However, her experience on a wilderness search and rescue squad opened her eyes to a love of clinical medicine, leading her to pursue an MD/PhD instead. 

Her graduate work on the genetics of inherited immune cancers guided her toward pediatrics, but she soon discovered that looking in ears and freezing warts wasn’t her calling. Still, knowing that pediatrics was where she truly felt at home made it easy to specialize once she chose to pursue anesthesiology. 


Responses have been edited for flow, clarity, and style. 

What drew you to this particular research question or problem? 

As a pediatrician, it was very clear to me that many of my patients and their loved ones had very little understanding of how much control they actually had over the way their bodies respond to health challenges, particularly those related to procedures and surgery. The field of Integrative Medicine addresses this directly, but its utility in the perioperative space has long been underutilized. As someone who understood both pediatrics and anesthesia, bringing this field into our arena was clearly the right thing to do — but you can’t convince anyone without evidence. Hence, the research. 

What impact do you hope this work will have on clinical practice, education, or society in general? 

Using co-design and co-selection strategies to create a mobile prehabilitation app for children and adolescents is something that has not been done before. My hope is that this study will demonstrate that patient- and family-centered product development is not only feasible, but in many cases preferable to the medical system’s usual prescriptive approach to preparing young people for surgery. I also hope that this app will empower children, adolescents, and families in BC and the Yukon (and beyond) by giving them more agency over how their bodies respond to periprocedural stress. Through simple, engaging, and enjoyable integrative techniques, the app aims to teach and guide users in ways that support their well-being throughout the surgical journey. 

Outside of work, what do you enjoy the most? 

Outside of work, I love spending time with my family traveling, skiing, hiking, cycling and running. As long as I am outside, I am happy! 


Research in Focus: Donald Griesdale 

Research in Focus shines a light on the innovative studies and discoveries taking shape across the UBC Department of Anesthesiology, Pharmacology & Therapeutics. Through each feature, we celebrate the minds driving meaningful change in research, education, and clinical practice across anesthesiology, pharmacology, and therapeutics. 

When patients with acute respiratory distress syndrome (ARDS) become critically ill, VV-ECMO can be the lifesaving therapy that keeps them alive. However, starting this powerful form of life support may also place unexpected stress on the brain. 

This prospective study by Dr. Donald Griesdale and his team investigates the mechanisms of brain injury in ARDS patients who require veno-venous extracorporeal membrane oxygenation (VV-ECMO). When VV-ECMO is initiated, it can cause a sudden and steep drop in arterial carbon dioxide (PaCO₂). This rapid change may trigger cerebral vasoconstriction, reducing blood flow to the brain and potentially leading to ischemic injury. 

To capture what happens in the brain at the exact moment VV-ECMO begins, the study uses robotic transcranial Doppler ultrasound to continuously measure middle cerebral artery flow velocity, providing real-time data on cerebral blood flow changes. At the same time, blood samples are collected to assess biomarkers of neurologic injury (GFAP, NF-L, tau, UCH-L1), and neuroimaging and neurocognitive follow-up help map the long-term clinical impact. 

The INFORM study aims to determine whether PaCO₂-related reductions in cerebral blood flow mediate neurologic injury, and ultimately to guide safer management strategies for VV-ECMO patients. By integrating critical care, neurophysiology, and translational neuroscience, this work seeks to improve neurologic outcomes for those facing severe respiratory failure. 

“I love working with diverse researchers and teams to tackle a variety of problems. That’s particularly why I love clinical epidemiology.”  

— Donald Griesdale, Associate Professor, UBC 

 


Meet Donald Griesdale! 

SiteVancouver General Hospital (VGH)   

Rank: Associate Professor 

Dr. Griesdale is the associate director of the Centre for Clinical Epidemiology and Evaluation and an intensive care physician at VGH. He is also an assistant professor in the UBC Department of Anesthesiology, Pharmacology and Therapeutics with cross appointments in the UBC Department of Medicine, Division of Critical Care Medicine and Neurology.  

Following his clinical training, Dr. Griesdale completed a Master of Public Health with a focus in Clinical Epidemiology. He has been fortunate to practice at the intersection of care delivery and research. 


Responses have been edited for flow, clarity, and style. 

What drew you to this particular research question or problem?

I’ve always enjoyed trying to understand the link between physiology and outcomes. The data underpinning the association between PaCO₂ and neurologic injury is tenuous at best. Thus, actually examining cerebral flow velocity as a surrogate for blood flow during cannulation for ECMO was an opportunity we couldn’t pass up. 

What surprised you the most in this study?

The most surprising aspect of this project was the willingness of the entire team to perform TCD while patients were being cannulated for ECMO. I’m grateful to my colleagues for allowing me to explore this area of inquiry and for being so supportive throughout the journey. 

Outside of work, what do you enjoy the most? 

I have three boys aged 20, 16, and 14. Along with my wife Peggy, we love to do outdoor activities like camping and hiking. I also love landscape, street, and wildlife photography. 

What’s been the most rewarding moment in your research journey so far? 

Honestly, I love working with diverse researchers and teams to tackle a wide variety of problems. That’s particularly why I enjoy clinical epidemiology — there are so many different approaches you can use. I also enjoy learning about different quantitative and qualitative methods. 


Faculty Spotlight: Navraj Chima  

The Faculty & Trainee Spotlight Series shines a light on the incredible people who make up the heart of UBC Department of Anesthesiology, Pharmacology & Therapeutics. Amidst the remarkable achievements and developments within the department, it is a pleasure to share the stories of the dynamic trainees and faculty who bring passion, curiosity, and insight that drive the areas of anesthesiology, pharmacology, and therapeutics forward. 


Meet Dr. Navraj Chima! 

Role: Clinical Assistant Professor 

Site: Vancouver General Hospital (VGH)

Dr. Navraj Chima completed his undergraduate degree in Microbiology at the University of Victoria before beginning medical school at UBC in 2009. He entered the UBC residency program, finishing in 2018 and subsequently starting a staff position at Vancouver General Hospital. 

When the COVID-19 pandemic disrupted his original fellowship plans, Dr. Chima went on to complete a fellowship in Trauma Anesthesia and POCUS at Toronto’s Sunnybrook Hospital in 2020–2021. 

He currently works at Vancouver General Hospital (VGH) and UBC Hospital, manages the perioperative fellowship program, and co-leads the Division of Trauma Anesthesia. He also serves as the undergraduate anesthesia co-director for the UBC Faculty of Medicine. 

“We truly work at the intersection of multiple specialties, which keeps the medicine fresh and interesting. ”  

— Navraj Chima, Clinical Assistant Professor, UBC 


Responses have been edited for flow, clarity, and style. 

How did your career path lead you to UBC and to your current position? 

During my medical training, both undergraduate and postgraduate, I have always enjoyed working with the staff at Vancouver General. The clinical environment is outstanding, and I couldn’t ask for a better group of colleagues. My interest in trauma began during my early days of first aid and paramedic training and was strengthened by the exceptional mentors I met along the way. I also developed an interest in clinical systems and how to improve them, which led to my passion for simulation training and medical education. 

What have you learned from working with residents and students that has surprised or inspired you? 

Residents and medical students are naturally inquisitive; they constantly push the boundaries of their knowledge as they study and learn our craft. This often leads to interesting conversations in the OR about patient care and clinical scenarios. You begin to see situations differently from how you first learned them, which in turn helps you adapt your teaching for future learners. 

What’s one piece of advice you received early in your career that has stayed with you? 

A physician I met early in my career once said, “Enjoy the bread and butter, but savour the zebras.” If you don’t appreciate the routine, everyday clinical cases, the rare and unusual ones won’t be enough to sustain your interest. That’s one of the things I love about anesthesia — there is so much variety in what we do, from case complexity to acuity to subspecialty. We truly work at the intersection of multiple specialties, which keeps the medicine fresh and interesting. 

If you weren’t in this field, what do you think you’d be doing instead? 

Another medical specialty I’ve always enjoyed is at the opposite end of the spectrum:  pathology. I loved lab work during undergrad and found the investigative aspect of pathology incredibly fascinating. If I were in a completely different professional field, I’d probably choose mechanical engineering, as I’m a big Formula One fan. But there’s also a part of me that could happily settle into being a museum curator, cataloguing and organizing exhibits and artifacts, uncovering ancient history, and sharing it with the community. 


Faculty Spotlight: Catrina Loucks

The Faculty & Trainee Spotlight Series shines a light on the incredible people who make up the heart of UBC Department of Anesthesiology, Pharmacology & Therapeutics. Amidst the remarkable achievements and developments within the department, it is a pleasure to share the stories of the dynamic trainees and faculty who bring passion, curiosity, and insight that drive the areas of anesthesiology, pharmacology, and therapeutics forward.


Meet Dr. Catrina Loucks!

Rank: Assistant Professor

During her BHSc/MSc at the University of Calgary, Dr. Loucks worked to uncover genetic causes of rare disorders under the supervision of Drs. Micheil Innes and Jillian Parboosingh. She then pursued a PhD at Simon Fraser University under the supervision of Dr. Michel Leroux, where she investigated the functional impacts of genetic mutations using the simple roundworm Caenorhabditis elegans as a model. Although these experiences provided her with valuable skills, she sought to gain expertise in genomics-based research in humans—an area presenting greater computational and statistical challenges, as well as opportunities for clinical intervention. To pursue this, she undertook a postdoctoral position at UBC.

“I am fortunate to work with wonderful trainees who inspire me every day with the unique skills and insights they bring to our research.”

— Catrina Loucks, Assistant Professor, UBC


Responses have been edited for flow, clarity, and style.

How did your career path lead you to UBC and to your current position?

As a postdoctoral fellow at UBC, I worked with Dr. Bruce Carleton and the Canadian Pharmacogenomics Network for Drug Safety to understand how genetic variation contributes to variable responses to medication. Overall, I have designed my research career to develop expertise in gene and mutation discovery, validation of genetic findings using the nematode model Caenorhabditis elegans, pharmacogenomic investigations, and the promotion of genomics-based precision medicine initiatives. I am now leveraging this unique combination of skills to lead the Loucks Pain Management Pharmacogenomics Lab in advancing optimized pain management strategies for children.

What do you find most rewarding about your work?

I am extraordinarily lucky to be able to continue in academia. I have always had a passion for genetics, and now my lab’s pipeline, from genetic discoveries to predictive genetic testing, has the power to help identify the safest and most effective medications for children. This is especially important in vulnerable patient populations, such as children with cancer and infants treated in the neonatal intensive care unit, who often experience significant pain requiring opioids. Overall, I am beyond grateful to have the opportunity to contribute to genetic research that has the potential to help children in pain.

What have you learned from working with residents and students that has surprised or inspired you?

I am fortunate to work with wonderful trainees who inspire me every day with the unique skills and insights they bring to our research. By leading a translational research program, I have been fortunate to attract trainees with expertise across pharmacogenomics, C. elegans genetics, medical genetics, molecular biology, genomics/bioinformatics, clinical pharmacology, and medicine. I continue to be amazed by the perspectives shaped by their diverse educational backgrounds which drive our work in novel and impactful directions I never would have envisioned on my own.

What’s one piece of advice you received early in your career that has stayed with you?

There is no single piece of advice I have received that has stayed with me on its own. Instead, I aspire to base my career on the examples set by the many excellent mentors and supervisors I have had over the years. Specifically, I strive to focus my efforts on research questions that genuinely spark my curiosity and passion, while also being meaningful to both my team and the individuals impacted by our work.


Trainee Spotlight: Annabel Chapman

The Faculty & Trainee Spotlight Series shines a light on the incredible people who make up the heart of UBC Department of Anesthesiology, Pharmacology & Therapeutics. Amidst the remarkable achievements and developments within the department, it is a pleasure to share the stories of the dynamic trainees and faculty who bring passion, curiosity, and insight that drive the areas of anesthesiology, pharmacology, and therapeutics forward. 


Meet Dr. Annabel Chapman! 

Role: Fellow 

Location: UBC Vancouver 

Throughout her BSc in Food Science and Nutrition and MSc in Human Nutrition, Annabel Chapman developed a strong interest in the social determinants of health and health equity. She went on to work in the UK charity sector, conducting community-based research focused on patients’ experiences within health and social care services. Wanting to return to academia, she pursued a PhD at the University of Brighton, where her research examined local shared values in communities in Senegal, Indonesia, and India to help inform socially acceptable nutrition interventions. This work ultimately led to her current research focus on implementation science and knowledge translation at UBC. 

“I am passionate about working with patients and community members to involve them in the research process and collaborate on co-designed projects.”  

— Annabel Chapman, Fellow, UBC 


How did your path lead you to UBC? 

During my PhD, working with communities to design more culturally appropriate interventions ignited my interest in intervention design and implementation, and deepened my passion for community-engaged work. I knew I wanted the next stage of my research career to focus on implementation science and knowledge translation, and I was also eager to gain experience outside of the UK. This led me to the Therapeutics Initiative at UBC, which happened to be advertising a postdoctoral position in implementation science—a perfect opportunity. 

What areas of research or practice are you most passionate about? 

I am passionate about working with patients and community members to involve them in the research process and collaborate on co-designed projects. This feels especially important when patients or community members come from groups that are seldom heard in research. Ultimately, partnering with patients can make research outputs more relevant and more effective. 

What do you enjoy doing outside of the hospital or lab? 

Enjoying the beautiful natural environment around Vancouver! I love to go for hikes in summer and to ski in winter. This year I am going to attempt to learn to snowboard. 

What’s a fun fact about you that most people wouldn’t guess? 

I’m from the Isle of Man! A place famous for motorbike races and cats with no tails. 


Dr. John Boyd Appointed as New Associate Professor and Recipient of the Professorship in Clinical Pharmacology and Therapeutics 

We are pleased to introduce Dr. John Boyd, a new full-time Associate Professor who joined our Department on October 1, 2025!

John holds a joint appointment between the Departments of Medicine and Anesthesiology, Pharmacology & Therapeutics, and is the inaugural recipient of the UBC Professorship in Clinical Pharmacology and Therapeutics. 

Dr. Boyd received his MD from the University of Western Ontario in 1998 and completed his Internal Medicine training there as well. He later pursued training in Pulmonary and Critical Care Medicine at McGill University from 2001 to 2004, followed by a Postdoctoral Fellowship at the Meakins Laboratory in Montreal from 2004 to 2005. He is currently an Intensivist in the St. Paul’s Hospital ICU and an Investigator with the Institute for Heart + Lung Health. In addition, he serves as the Medical Director of the Early Phase Clinical Trials Unit at Providence Health and holds the UBC Professorship in Clinical Pharmacology and Therapeutics. 

The Professorship in Clinical Pharmacology and Therapeutics 

The Professorship in Clinical Pharmacology and Therapeutics provides leadership in accelerating the province’s capacity to design, evaluate, and trial next-generation therapeutics, significantly expanding bio-innovation within the BC Life Sciences ecosystem. Situated within an exciting translational environment, key activities include participating in the design and execution of clinical trials—preferably early-stage trials—and leading the development of a residency program in clinical pharmacology. The Professorship also supports initiatives aimed at enhancing training and capacity-building in areas essential to sustaining BC’s ability to evaluate existing therapies and maintain long-term clinical trials infrastructure. 

The successful candidate is expected to offer academic leadership for the new Clinical Trials Unit (CTU) at the upcoming Providence campus and to lead an integrated research and education program in clinical pharmacology at UBC. 

Please join us in welcoming John to the Department! 

Research in Focus: Anshula Ambasta 

Research in Focus shines a light on the innovative studies and discoveries taking shape across the UBC Department of Anesthesiology, Pharmacology & Therapeutics. Through each feature, we celebrate the minds driving meaningful change in research, education, and clinical practice across anesthesiology, pharmacology, and therapeutics. 

Dr. Anshula Ambasta’s research applies the principles of quality improvement, patient safety, and implementation science to understand and modify current healthcare processes with the goal of improving patient outcomes. Her program uniquely combines patient engagement, large-scale quality improvement, and implementation science within healthcare operations, enabling real-time changes that enhance the delivery of care. 

“It is my ultimate hope that, through robust research defining evidence-based practice and effective implementation that ensures this evidence is integrated into clinical care, healthcare systems will become more seamless for providers, more patient-centered, and more efficient and sustainable for the future..”  

– Anshula Ambasta, Assistant Professor, UBC 


Meet Anshula Ambasta! 

Site: UBC  

Rank: Assistant Professor 

Dr. Ambasta is a clinician-scientist, working as a general internal medicine physician and a research faculty member in the Department of Anesthesiology, Pharmacology & Therapeutics at the University of British Columbia (UBC). Her clinical training as a general internal medicine specialist provided her with insight into healthcare system processes and opportunities to make care safer, more effective, and patient-centered. She further strengthened her expertise with a Master of Public Health from Harvard University, equipping her with the epidemiological and research skills needed to critically analyze health system challenges and co-develop solutions with stakeholders that are both effective and patient-focused. 


Responses have been edited for flow, clarity, and style.

What drew you to this particular research question or problem? 

As a front-line clinician, I am passionate about ensuring that people receive timely, appropriate, and evidence-based care that aligns with their values and priorities. In my research role, I am fortunate to work with teams of researchers, clinicians, and individuals with lived experience navigating healthcare systems to identify opportunities for improvement and to develop and test interventions. 

What’s been the most rewarding moment in your research journey so far? 

One of the research projects I am currently working on focuses on the appropriate use of laboratory testing in hospitalized patients. As part of this project, I have been integrating information about testing appropriateness into the residency education system and empowering patients to engage in their care. One of the most rewarding moments came when a resident physician, unaware of my role in the project, spoke about the program and its importance in ensuring tests are ordered appropriately. Similarly, I felt grateful when patients referenced the educational resources developed as part of the program and asked questions about their hospital testing. 

Outside of work, what do you enjoy the most? 

Outside of work I enjoy the outdoors (hiking and biking with my partner and two kids), reading books, and dancing. 

What impact do you hope this work will have on clinical practice, education, or society in general? 

It is my ultimate hope that, through robust research defining evidence-based practice and effective implementation that ensures this evidence is integrated into clinical care, healthcare systems will become more seamless for providers—supported with the knowledge and confidence needed for decision-making—more patient-centered, where patients are empowered to ask questions and express their values and preferences—and more efficient and sustainable for the future. 


Trainee Spotlight: Wesam Farag

The Faculty & Trainee Spotlight Series shines a light on the incredible people who make up the heart of UBC Department of Anesthesiology, Pharmacology & Therapeutics. Amidst the remarkable achievements and developments within the department, it is a pleasure to share the stories of the dynamic trainees and faculty who bring passion, curiosity, and insight that drive the areas of anesthesiology, pharmacology, and therapeutics forward. 


Meet Dr. Wesam Farag! 

Location: UBC  

Wesam is a pharmacist by training. He earned his BSc in Pharmaceutical Sciences and MSc in Pharmacology from Alexandria University in Egypt, followed by a PhD in Pharmacology from the University of Alberta, Canada. After completing his doctoral studies, Wesam joined the University of British Columbia as a postdoctoral fellow in Dr. Khaled Abdelrahman’s lab, where he explores the molecular and cellular mechanisms underlying neurodegenerative diseases, particularly Alzheimer’s disease. 

During his PhD, Wesam investigated molecular biology and the pathophysiological mechanisms contributing to disease development, focusing on targeting specific cellular molecules to modulate cardiac disorders. Although his current research centers on neuropharmacology and Alzheimer’s pathophysiology, the expertise he developed during his PhD has equipped him with the knowledge and skills needed for his current work, supported by the advanced resources of the Abdelrahman Lab and the training opportunities available at UBC. 

“The opportunity to conduct research in neuropharmacology at one of the leading institutes in Canada, alongside some of the most brilliant and accomplished scientists in the field, has been a major milestone in my scientific career.”  

— Wesam Farag, Postdoctoral Fellow, UBC 


Responses have been edited for flow, clarity, and style.

What inspired you to pursue anesthesiology, pharmacology, or therapeutics? 

Growing up in a family of scientists, I have always aspired to pursue an academic career as an independent investigator, conducting my own research and inspiring the next generation of scientists. My studies in pharmacology as an undergraduate sparked a passion for understanding how drugs work at the molecular level and how targeting specific cellular pathways can advance therapeutic discovery—a path I have been eager to follow since pharmacy school. Witnessing close relatives and friends suffer from Alzheimer’s disease deepened my commitment to neuroscience research. I hope to contribute meaningfully to uncovering the mechanisms underlying these devastating diseases and advancing our understanding toward potential treatments.

What areas of research or practice are you most passionate about? 

I have always been interested in the field of neuropharmacology and in contributing to this scientific community by playing a key role in unraveling the pathophysiological mechanisms of neurodegenerative disorders and developing better therapeutic options for their management. The opportunity to conduct research in neuropharmacology at one of the leading institutes in Canada, alongside some of the most brilliant and accomplished scientists in the field, has been a major milestone in my scientific career. It has further strengthened my skills and advanced my goal of becoming an independent researcher. With the support, resources, and excellent training environment provided by the Abdelrahman Lab, this interest has begun to define my career path. 

It has also been a great honor to receive two distinguished fellowships to support my postdoctoral training—the Canadian Institutes of Health Research (CIHR) Postdoctoral Fellowship and the Michael Smith Health Research BC/Alzheimer Society of BC Research Trainee Award—which are helping me pursue my research and take meaningful steps toward achieving my career goals. 

What has surprised you most about your training? 

When I came to Vancouver, I was captivated by the city’s beauty, its rich cultural diversity, and the highly competitive spirit of scientists and students at UBC, all striving to provide and acquire the highest level of knowledge. Since beginning my fellowship, I have received extensive training in many advanced techniques used in the field, including astrocyte isolation from mice, behavioral animal assessment, and laser speckle imaging. The training environment in the Abdelrahman Lab has offered comprehensive support and infrastructure, enabling the successful development and execution of my research goals. 

As part of the Department of Anesthesiology, Pharmacology & Therapeutics, I have had the opportunity to collaborate with interdisciplinary teams and leading neuroscientists and vascular biologists within the Faculty of Medicine. This experience has strengthened my research skills and connected me to the broader scientific community. 

What do you enjoy doing outside of the hospital or lab? 

Outside the lab, I enjoy exploring the beauty of British Columbia, spending time with my family and enriching my knowledge as a pharmacist and pharmacologist by keeping up with the latest news and the newly published articles in the field. 


Research in Focus: Janny Ke

Research in Focus shines a light on the innovative studies and discoveries taking shape across the UBC Department of Anesthesiology, Pharmacology & Therapeutics. Through each feature, we celebrate the minds driving meaningful change in research, education, and clinical practice across anesthesiology, pharmacology, and therapeutics. 

Dr. Janny Ke and her team have developed predictive models that could transform how doctors monitor patients after elective colectomy. Using data from over 130,000 patients in the National Surgical Quality Improvement Program between 2014 and 2019, they created and validated time-to-event models to forecast major medical complications within 30 days of surgery. 

Their analysis revealed striking differences in when complications typically occur: while bleeding requiring transfusion tended to happen almost immediately (within the first day after surgery), conditions like venous thromboembolism appeared much later, around 12 days postoperatively. Complication rates ranged from as low as 0.3% for cardiac arrest and acute renal failure to 5.3% for bleeding requiring transfusion, with an overall readmission rate of 8.6%. 

The models showed strong predictive power for mortality, myocardial infarction, pneumonia, and renal failure, but were less accurate for readmission, venous thromboembolism, and sepsis. Once further validated, these tools could help clinicians identify high-risk patients and tailor monitoring to the periods when they are most vulnerable, potentially improving outcomes after surgery. 

“Accurate risk prediction that responds to a patient’s perioperative course can help create monitoring plans tailored to individual risks and periods of vulnerability, optimizing both healthcare resources and outcomes.”  

— Janny Ke, Clinical Assistant Professor, UBC 


Meet Janny Ke! 

Site: Providence Healthcare   

Rank: Clinical Assistant Professor 

Dr. Ke has always been passionate about research. Curious about the integration of artificial intelligence in medicine, she completed a Master of Science in Epidemiology, focusing on Big Data, prediction modeling, and population studies through her thesis and coursework. She credits numerous research mentors for their guidance throughout her career, particularly during her residency at Dalhousie, her Master’s program, and her work at UBC. 


Responses have been edited for flow, clarity, and style.

What’s one thing you hope people will take away from this study? 

This was a proof-of-concept set of models designed to predict not only who may experience complications, but also when those complications might occur. While some models performed well, others did not. Additional high-quality clinical data are needed to improve our ability to develop and evaluate prediction models. 

How does this project fit into your broader research interests or goals? 

Accurate risk prediction that responds to a patient’s perioperative course can help create monitoring plans tailored to individual risks and periods of vulnerability, optimizing both healthcare resources and outcomes. This capability is likely to improve with the use of artificial intelligence. However, prediction models require high-quality clinical data—which is often lacking—as well as rigorous validation and assessment to ensure accuracy and equity. As artificial intelligence becomes more integrated into risk prediction, clinician involvement in model development is essential. Education and standardization are also needed to enable clinicians to interpret and use these models effectively, while remaining aware of their limitations and potential biases. 

Outside of work, what do you enjoy the most? 

I love hiking, climbing, painting, and playing the piano, though these days I’m mostly bossed around by toddlers. 


Read the publication: Development and internal validation of time-to-event risk prediction models for major medical complications within 30 days after elective colectomy


Faculty Spotlight: Sandy Kisilevsky

The Faculty & Trainee Spotlight Series shines a light on the incredible people who make up the heart of UBC Department of Anesthesiology, Pharmacology & Therapeutics. Amidst the remarkable achievements and developments within the department, it is a pleasure to share the stories of the dynamic trainees and faculty who bring passion, curiosity, and insight that drive the areas of anesthesiology, pharmacology, and therapeutics forward.


Meet Dr. Sandy Kisilevsky!

Role: Clinical Assistant Professor

Dr. Sandy Kisilevsky spent four amazing years as an undergraduate at Queen’s University before travelling abroad, where she fell in love and married a Glaswegian doctor. After his passing, she became preoccupied with studying medicine. She went on to complete an MD-PhD in Calgary and was introduced to anesthesiology through a friend’s recommendation. Drawn to Vancouver for its climate and mountains, she pursued her residency there, and a key mentor sparked her passion for neuroanesthesiology. After completing a fellowship in San Francisco, Dr. Kisilevsky joined Vancouver General Hospital (VGH), where she has served as a consultant anesthesiologist for the past decade and as the co-head for the UBC division of neuroanesthesiology.

“It is exciting, intellectually stimulating, and immensely rewarding to care for some of the sickest patients in the province.”

— Sandy Kisilevsky, Clinical Assistant Professor, UBC


Responses have been edited for flow, clarity, and style.

What drew you to anesthesiology/pharmacology/therapeutics as a specialty or area of research?

My first direct exposure to anesthesiology came during a medical student elective in Hay River, Northwest Territories. My attending physician turned out to be a final-year anesthesiology resident on a rural locum, and I watched him alleviate the pain of a memorable emergency department (ED) patient using regional anesthesia. Later, my family practice preceptor, a late-career general practitioner (GP) anesthetist, described pursuing general practice anesthesia (GPA) training after delivering general anesthesia in an emergency rural setting, guided over the telephone by the on-call anesthesiologist who had not yet arrived. These individuals were particularly inspiring to me. Witnessing an above-knee amputation performed under spinal anesthesia, with the patient fully awake, ultimately solidified my decision: I needed to understand how this was possible.

What do you find most rewarding about your work?

As a mid-career anesthesiologist, I love all aspects of my work at VGH. It is exciting, intellectually stimulating, and immensely rewarding to care for some of the sickest patients in the province. I enjoy building rapport with them and safely guiding them through their perioperative journey. My anesthesiologist colleagues are another major source of enjoyment—they are an outstanding group who foster a sociable work environment filled with interesting and often humorous conversations. I feel incredibly fortunate to have a job I love that also allows me to raise my children in beautiful Vancouver, BC.

If you weren’t in this field, what do you think you’d be doing instead?

I would have been a forensic scientist. As a child, long before CSI popularized the field, my dad gave me books on real-life cases solved through forensics. The Arsenic Milkshake was my favourite. I went on to earn my Master’s degree from the internationally renowned forensic program at the University of Strathclyde in Scotland. During my degree, I conducted research with the RCMP Forensic Unit in Regina, and my thesis focused on DNA profiling of epithelial cells transferred to handled objects, now an established technique in crime scene investigation. After completing my training, I was offered a position with the RCMP forensic unit in Ottawa, but I ultimately turned it down to pursue medicine.

What’s one piece of advice you received early in your career that has stayed with you?

“Let learners try.”

As a consultant anesthesiologist in a large academic teaching centre, I have the pleasure of working with medical students and residents at all levels of training. It is my responsibility to strike a balance between providing learners with an appropriate level of independence while maintaining the highest standard of patient safety