The 2018 Anesthesiology, Pharmacology & Therapeutics Research Day 2018 Guest Lecture is available here
“Clinical Pharmacology – A Journey from Michael Jackson to TensorFlow”
Steven L. Shafer, MD
Professor of Anesthesiology, Perioperative and Pain Medicine, Stanford University
Adjunct Associate Professor of Bioengineering and Therapeutic Sciences, UCSF
Dr. Shafer’s professional interests are the clinical pharmacology of intravenous anesthetic drugs, opioids and hypnotics used in anesthetic practice. However, his real passion is not the drugs themselves, but rather the mathematical models that characterize drug behavior. These include conventional pharmacokinetic and pharmacodynamic models, inverse models (used to drive target controlled infusion systems), Bayesian models (used to handle model uncertainty), pharmacokinetic and pharmacodynamic models of drug interaction, models of receptor function that help elucidate mechanisms of drug action, and models that relate drug response to “in silico” pharmacogenetics.