Dr. Sastry Bhagavatula, M.Pharm., M.Sc., Ph.D.

Professor – Anesthesiology, Pharmacology and Therapeutics

Department of Anesthesiology, Pharmacology and Therapeutics

Contact Information:

Email: sastry@mail.ubc.ca
Ph: 604-822-2290

Research Interests

Plasticity of synaptic transmission – mechanisms and age-related aspects.

Recent interests include the examination of mechanisms involved in the plasticity of GABA-ergic synaptic transmission in the mammalian central nervous system. We are also analyzing age-relatedness of this plasticity.

Dr. Sastry’s research has been funded by grants from the National Institutes of Health, USA.

Representative Publications:

1. M. Ouardouz and B. R. Sastry
Mechanisms underlying LTP of inhibitory synaptic transmission in the deep cerebellar nuclei.
J. Neurophysiol. 84: 1414-1421, 2000.

2. W. Morishita and B. R. Sastry
Postsynaptic mechanisms underlying long-term depression of GABAergic transmission in neurons of the deep cerebellar nuclei.
J. Neurophysiol. 76: 59-68, 1996.

3. T. Shew, S. Yip and B. R. Sastry
Mechanisms involved in tetanus-induced potentiation of fast IPSCs in rat hippocampal neurons.
J. Neurophysiol. 83: 3388-3401, 2000.

4. B. R. Sastry and L. S. Bhagavatula
Quantal release of transmitter at a central synapse.
Neuroscience 75: 987-992, 1996.

5. B. R. Sastry, J. W. Goh and A. Auyeung
Associative induction of post-tetanic and long-term potentiation in CA1 neurons of rat hippocampus.
Science 232: 988-990, 1986.

The Vancouver Biomedical Research Foundation (VBHRF)

The foundation is dedicated to pursuing as well as organizing discussions on research in biomedical and health fields, and in enhancing public awareness of science. B. R. Sastry is the founder and the current director of this foundation. VBHRF has organized three international symposia in Vancouver during the last three years. A number of internationally well-known scientists participated in these symposia.